See How Tetramers Have Been Used A collection of science publications featuring work with tetramers. Biomarkers for Antigen Immunotherapy in Allergy and Type 1 Diabetes Odegard J, Nepom GT and Wambre E. Clin Immunol.. 2016. 44-50(161) PMID: PMCID: PMC4628579 DOI: 10.1016/j.clim.2015.05.023 Read more about Biomarkers for Antigen Immunotherapy in Allergy and Type 1 Diabetes Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining Uchtenhagen H, Rims C, Blahnik G, Chow IT, Kwok WW, Buckner JH, James EA.. Nat Commun. 2016. 12614(7) PMID: PMCID: PMC5013714 DOI: 10.1038/ncomms12614 Read more about Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining Ana o 1 and Ana o 2 cashew allergens share cross-reactive CD4+ T-cell epitopes with other tree nuts Archila LD, Chow IT, McGinty JW, Renand A, Jeong D, Robinson D, Farrington ML, Kwok WW. Clin Exp Allergy. 2016. 871-883(46) PMID: PMCID: PMC5013714 DOI: 10.1111/cea.12746 Read more about Ana o 1 and Ana o 2 cashew allergens share cross-reactive CD4+ T-cell epitopes with other tree nuts Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome James EA, Gates TJ, LaFond RE, Yamamoto S, Ni C, Mai D, Gersuk VH, O'Brien K, Nguyen QA, Zeitner B, Lanteri MC, Norris PJ, Chaussabel D, Malhotra U, Kwok WW.. PLoS Pathog. 2016. 1(12) PMID: PMCID: PMC4721872 DOI: 10.1371/journal.ppat.1005375 Read more about Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with allergen-specific modulation of immune reactivity Hinz D, Seumois G, Gholami A, Greenbaum J, Lane J, White B, Broide D, Schulten V, Sidney J, Bakhru P, Oseroff C, Wambre E, James EA, Kwok W, Peters B, Vijayanand P, Sette A.. Clin Exp Allergy. 2016. 705-719(46) PMID: PMCID: PMC4721872 DOI: 10.1111/cea.12692 Read more about Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with allergen-specific modulation of immune reactivity Jug r 2-reactive CD4+ T-cells have a dominant immune role in walnut allergy Archila LD, Jeong D, Pascal M, Bartra J, Juan M, Robinson D, Farrington ML, Kwok WW.. J Allergy Clin Immunol.. 2015. 983-992(136) PMID: PMCID: PMC4568181 DOI: 10.1016/j.jaci.2015.01.029 Read more about Jug r 2-reactive CD4+ T-cells have a dominant immune role in walnut allergy Chronic cat-allergen exposure induces a TH2 cell-dependent IgG4 response related to low-sensitization Renand A, Archila LD, McGinty J, Wambre E, Robinson D, Hales BJ, Thomas WR, Kwok WW.. J Allergy Clin Immunol. 2015. 1627-1635(136) PMID: PMCID: PMC4721872 DOI: 10.1016/j.jaci.2015.07.031 Read more about Chronic cat-allergen exposure induces a TH2 cell-dependent IgG4 response related to low-sensitization Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner. Wambre E, DeLong JH, James EA, Torres-Chinn N, Pfützner W, Möbs C, Durham SR, Till SJ, Robinson D, Kwok WW. J Allergy Clin Immunol. 2014. 872-9(3) PMID: 24373351 DOI: 10.1016/j.jaci.2013.10.054 Read more about Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner. Grass-specific CD4+ T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy Archila LD, DeLong JH, Wambre E, James EA, Robinson DM, Kwok WW.. Clin Exp Allergy. 2014. 986-998(44) PMID: PMCID: PMC4069242 DOI: 10.1111/cea.12324 Read more about Grass-specific CD4+ T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy T-cell responses over time in a mild hemophilia A inhibitor subject: epitope identification and transient immunogenicity of the corresponding self-peptide James EA, Kwok WW, Ettinger RA, Thompson AR, Pratt KP. J Thromb Haemost. 2007. 2399-407(5) PMID: 18034765 Read more about T-cell responses over time in a mild hemophilia A inhibitor subject: epitope identification and transient immunogenicity of the corresponding self-peptide
Biomarkers for Antigen Immunotherapy in Allergy and Type 1 Diabetes Odegard J, Nepom GT and Wambre E. Clin Immunol.. 2016. 44-50(161) PMID: PMCID: PMC4628579 DOI: 10.1016/j.clim.2015.05.023 Read more about Biomarkers for Antigen Immunotherapy in Allergy and Type 1 Diabetes Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining Uchtenhagen H, Rims C, Blahnik G, Chow IT, Kwok WW, Buckner JH, James EA.. Nat Commun. 2016. 12614(7) PMID: PMCID: PMC5013714 DOI: 10.1038/ncomms12614 Read more about Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining Ana o 1 and Ana o 2 cashew allergens share cross-reactive CD4+ T-cell epitopes with other tree nuts Archila LD, Chow IT, McGinty JW, Renand A, Jeong D, Robinson D, Farrington ML, Kwok WW. Clin Exp Allergy. 2016. 871-883(46) PMID: PMCID: PMC5013714 DOI: 10.1111/cea.12746 Read more about Ana o 1 and Ana o 2 cashew allergens share cross-reactive CD4+ T-cell epitopes with other tree nuts Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome James EA, Gates TJ, LaFond RE, Yamamoto S, Ni C, Mai D, Gersuk VH, O'Brien K, Nguyen QA, Zeitner B, Lanteri MC, Norris PJ, Chaussabel D, Malhotra U, Kwok WW.. PLoS Pathog. 2016. 1(12) PMID: PMCID: PMC4721872 DOI: 10.1371/journal.ppat.1005375 Read more about Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with allergen-specific modulation of immune reactivity Hinz D, Seumois G, Gholami A, Greenbaum J, Lane J, White B, Broide D, Schulten V, Sidney J, Bakhru P, Oseroff C, Wambre E, James EA, Kwok W, Peters B, Vijayanand P, Sette A.. Clin Exp Allergy. 2016. 705-719(46) PMID: PMCID: PMC4721872 DOI: 10.1111/cea.12692 Read more about Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with allergen-specific modulation of immune reactivity Jug r 2-reactive CD4+ T-cells have a dominant immune role in walnut allergy Archila LD, Jeong D, Pascal M, Bartra J, Juan M, Robinson D, Farrington ML, Kwok WW.. J Allergy Clin Immunol.. 2015. 983-992(136) PMID: PMCID: PMC4568181 DOI: 10.1016/j.jaci.2015.01.029 Read more about Jug r 2-reactive CD4+ T-cells have a dominant immune role in walnut allergy Chronic cat-allergen exposure induces a TH2 cell-dependent IgG4 response related to low-sensitization Renand A, Archila LD, McGinty J, Wambre E, Robinson D, Hales BJ, Thomas WR, Kwok WW.. J Allergy Clin Immunol. 2015. 1627-1635(136) PMID: PMCID: PMC4721872 DOI: 10.1016/j.jaci.2015.07.031 Read more about Chronic cat-allergen exposure induces a TH2 cell-dependent IgG4 response related to low-sensitization Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner. Wambre E, DeLong JH, James EA, Torres-Chinn N, Pfützner W, Möbs C, Durham SR, Till SJ, Robinson D, Kwok WW. J Allergy Clin Immunol. 2014. 872-9(3) PMID: 24373351 DOI: 10.1016/j.jaci.2013.10.054 Read more about Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner. Grass-specific CD4+ T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy Archila LD, DeLong JH, Wambre E, James EA, Robinson DM, Kwok WW.. Clin Exp Allergy. 2014. 986-998(44) PMID: PMCID: PMC4069242 DOI: 10.1111/cea.12324 Read more about Grass-specific CD4+ T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy T-cell responses over time in a mild hemophilia A inhibitor subject: epitope identification and transient immunogenicity of the corresponding self-peptide James EA, Kwok WW, Ettinger RA, Thompson AR, Pratt KP. J Thromb Haemost. 2007. 2399-407(5) PMID: 18034765 Read more about T-cell responses over time in a mild hemophilia A inhibitor subject: epitope identification and transient immunogenicity of the corresponding self-peptide